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A link has been found between brittle bones and the risk of heart disease in women.
Osteoporosis increases the risk of fracture
A study by US researchers shows women who have early signs of osteoporosis are
up to five times more likely to have damaged arteries than those with healthy
bones.
The association was so strong that low bone density was a stronger predictor of
heart disease than major risk factors such as high blood pressure, diabetes or a
family history of heart disease.
This is believed to be the first time the bone-wasting illness has been linked
with cardiac disease.
But the findings do fit with earlier research suggesting women taking vitamin D
supplements to protect against thinning bones also see a decline in heart
attacks.
Dr Hillary Tran, from the William Beaumont Hospital in Royal Oak, Michigan,
said: "Our study is the first to report an increase in documented coronary
artery disease in patients with osteoporosis."
"The presence of osteoporosis predicts significant coronary stenosis, narrowing
of the arteries, with higher odds ratio than traditional risk factors."
Common condition
Osteoporosis affects one in three women and one in 12 men in the UK.
Although it is regarded as a disease of old age, research suggests its roots may
lie in adolescence.
Tens of thousands of more women are thought to have osteopenia - thinning of the
bones that puts them in danger of the disease.
Several risk factors, such as age, diabetes, high blood pressure and smoking,
can affect a woman's chances of getting both osteoporosis and heart disease.
Dr Tran and colleagues decided to investigate whether patients with one disease
were more likely to have the other.
They carried out bone scans and angiograms on 209 patients, most of them women,
over a two-year period.
Patients were split into groups according to whether they had normal bone
density, osteopenia, or full-blown osteoporosis.
The results showed women who had early signs of bone disease were five times
more likely than healthy volunteers to have damaged blood vessels.
For those with a family history of cardiac disease, the risk was 2.79 times
greater and if they had high blood pressure, it was 2.3 times higher.
Other tests showed those with low bone density were likely to have a greater
number of damaged blood vessels than women with normal bones.
The reason why thinning bones may be a marker for heart disease remains unclear
but Dr Tran said more research is needed to investigate the relationship.
The results were presented at the annual meeting of the American College of
Cardiology in Chicago.
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